Thank you!
It was essential for me to know, that the media folder in the reverse proxy is optional.
I have tried to use nginx proxy manager bypassing caddy.
I had two small obstacles to overcome.
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seahub was bound on connections from localhost. This resulted in “no response” error. Binding needed to be changed according to Seafile 7 only listens to 127.0.0.1 - #7 by vmajor
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external url led to csrf error when logging in. Url needs to be allowed according to Upgrade notes for 11.0.x - Seafile Admin Manual
Now it works! Thanks a lot