Using a Single Database

In principle, the clear separation of ccnet_db, seafile_db, and seahub_db (standard installation) is understandable. However, I wanted to ask if anyone has long-term experience with merging all three databases into one.
The databases have tables with unique names, so I assume there should be no conflicts.

Nevertheless, I would like to know beforehand if it could lead to any problems. Can I use a single database without concerns?